In the deep exploration of contemporary molecular biology, complementary DNA (cDNA) has become the core factor to promote the development of multi-dimensional research with its excellent characteristics. With the deepening study of gene expression regulatory network, functional genomics framework and molecular pathological mechanism of diseases, the limitations of traditional research strategies in the face of […]
Fungi are a kind of magical creatures. They are in various forms, from microscopic yeasts to mushrooms and fungus visible to the naked eye. It is not only different from the photosynthesis of plants, but also different from the feeding mode of animals. It survives by absorbing nutrients from the surrounding environment. Widely distributed in […]
Eubacteria belong to the prokaryotic domain, with prokaryotic cell structure, nuclear wrapped by nuclear membrane, and genetic material DNA exposed in the quasi-nuclear region. Binary fission is the main breeding mode, and some of them can form spores to resist adversity in harsh environment. Metabolic types are diverse, including photoautotrophic, chemoautotrophic, photoheterotrophic and chemoheterotrophic. Respiratory […]
Eubacteria, as an ancient and diverse microbial group on the earth, are widely distributed in every corner of our lives. From hot springs to cold polar regions, from fertile soil to deep oceans, there are traces of them. Although this kind of prokaryote is small, it occupies an irreplaceable key position in the operation of […]
Introduction to Cancer Molecular Markers Cancer, as a group of complex and prevalent diseases, has always been the focus of biomedical research. In cancer research, molecular markers, as important biomarkers, provide strong support for the early diagnosis, prognosis, and treatment selection of cancer. Molecular markers, at the level of genes, proteins, or metabolites, are specific […]
Plant RNA Extraction Overview In the extensive domain of molecular biology, the extraction of RNA from plants is recognized as a fundamental procedure in the study of gene expression, functional genomics, and transcriptomics. RNA,a conduit for genetic information, plays a pivotal role in various aspects of plant growth, development, and response to environmental stresses. However, […]
The integration of molecular markers into plant breeding traces its origins to the late 20th century, when advancements in molecular biology began to unravel the genetic architecture of crops. Early efforts focused on restriction fragment length polymorphisms (RFLPs), which provided the first glimpses into genetic diversity at the DNA level. Over decades, this field has […]
In contemporary biological research, the handling of high-dimensional data has emerged as a significant challenge. For instance, in the analysis of microbial communities and gene expression data, samples often encompass thousands of features (such as Operational Taxonomic Units (OTUs) or gene expression values). Direct analysis of these high-dimensional datasets not only involves substantial computational effort […]
In the realm of genomics research, the error rate serves as a critical indicator of the reliability associated with sequencing technologies. Elevated error rates can result in false positive or false negative variant detections, consequently affecting the completeness and accuracy of genome assembly. PacBio and Nanopore are two prominent representatives of long-read sequencing technologies that […]
RNA virus belongs to the first class of virus classification, and its core feature is that the genetic material is RNA rather than DNA. This kind of virus widely exists in nature, including many pathogens that have great influence on human health, such as influenza virus, HIV, novel coronavirus (SARS-CoV-2) and so on. According to […]
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