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Population Evolution
Population Evolution
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Population Evolution

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Introduction to population evolution

Population evolution research refers to obtaining variation information such as SNPs, InDels, SVs, CNVs of each subgroup in a certain natural population of particular species through different sequencing methods. Then, based on the population variation information, analyze the population's genetic diversity, genetic structure, gene flow, species formation mechanism, and population dynamic evolution and other biological issues, and in-depth study of the evolution of the species from the molecular level.

Scope of application

  • Research on the mechanism of artificial domestication
  • The genetic relationship of wild-type and domesticated populations was inferred through genetic analysis of the two populations, then key genes related to important economics traits were identified, which provided good guidance for the agricultural breeding of animals and plants

  • Analysis of natural selection mechanism
  • The genes selected in the adaptive evolution process can be unearthed through the research of populations from different geographical areas, then providing environmental adaptive genetic resources for breeding work.

  • Population history research
  • By analyzing the possible origin of the species and genetic variation information of the population in each distribution area, the evolution process of the species can be explored.

Sample requirements

  • Different subspecies and lines of the same species
  • Groups of different geographical distributions
  • at least 10 samples for each group, and the total sample size should be no less than 30

Workflow of population evolution

Workflow of population evolution

Advantages and features

  • Extensive multiplexing flexibility and high-throughput sequencing, enables for detecting large number of SNPs, InDels, CNVs, CVs.
  • Time and cost efficient.
  • Dedicate support from specialized PhD-level scientists.

References:

  1. Nadeau N J, Ruiz M, Salazar P, et al. Population genomics of parallel hybrid zones in the mimetic butterflies, H. melpomene and H. erato[J]. Genome Research. 2014, 24(8): 1316-1333.
  2. Tine M, Kuhl H, Gagnaire P A, et al. European sea bass genome and its variation provide insights into adaptation to euryhalinity and speciation[J]. Nature communications, 2014, 5.
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