Targeted RNA-sequencing selects and sequences subset transcripts of interests, increasing the coverage of a focused set of RNA sequences. It is an accurate method that generates genomic and gene-expression information of specific genome regions. The specific RNA sequences analysis enables RNA-Seq with high sensitivity and cost-effective access to NGS. By either targeted capture enrichment or amplicon-based approaches, Targeted RNA-Seq measures dozens to thousands of targets simultaneously. Enrichment assays also is a tool to identify both known and novel gene fusion partners in many sample types.
Providing qualitative and quantitative information for differential expression analysis, allele-specific expression measurement, and gene fusion verification, targeted RNA-sequencing can help to understand tumor classification and progression, genetic diseases and RNA drug response. Cancer transcriptome sequencing provides valuable information about gene expression changes in tumors. Profiling RNA-based drug response biomarkers aids too uncover multiple drug-susceptible tumorigenic pathways and improve the efficiency and success rate of the drug development process.
Advantages of Targeted RNA Sequencing
Targeted RNA Sequencing workflow
We offer integrated targeted RNA-Seq workflows that simplify the entire process, from library preparation to data analysis and biological interpretation.