CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Blog Archives

Sequencing Technologies and Applications in Microecology Research

Organisms live in an ecological context, and pure cultures rarely exist in nature. Microbial communities comprising microecology are one example of systems that are far from being pure culture which makes them dynamic in playing roles in the ecosystem.  Despite their abundance and ubiquity, our understanding of microecology, their interactions, and functions lag our knowledge […]

Fecal Microbiome Research: From Sampling to Sequencing

In recent years, studies have been progressively conducted to assess the effect of distinct sampling techniques on the outcomes of fecal microbiome assessment, in order to address this unmet need in the area of microbiome research. These methodology researches are useful for researchers to create quite rational guidelines for the procedure of fecal sampling, handling, […]

Efficient, Accurate, and Affordable, NGS Offers Great Choice for Antibiotic Gene Resistance

When bacteria, fungi, viruses, and parasites change over time and no longer respond to antibiotics, antimicrobial resistance (AMR) occurs. This makes an emerging issue related to the development and usage of antibiotics. Traditional microbial screening methods for AMR can be very laborious and time-consuming. However, the use of next-generation sequencing (NGS), especially whole-genome sequencing (WGS), […]

The Applications and Methods of Next-Generation Sequencing of SARS-CoV-2 on COVID-19 Research

Without previous understanding of organisms, next-generation sequencing (NGS) offers an efficient unbiased approach to determine new coronavirus strains and other pathogens. New variants of the SARS-CoV-2 coronavirus are increasingly concerned about the rapid spread, highlighting the necessity for more sequencing to rapidly identify mutations and limit the risk of new strains. Sequencing was employed early […]

CRISPR Screen Sequencing, An Innovative Sequencing Technology that Can Facilitate COVID-19 Research

Clustered regularly interspaced short palindromic repeats, or CRISPR, is one of the most phenomenal discoveries that paved the way for modern genome screening and editing technologies. CRISPR is a family of DNA found in the genome of prokaryotes, specifically bacteria and archaea. These sequences contain DNA fragments from known bacteriophages that infect the particular prokaryote. […]

Virus Sequencing, A Handy Method to Facilitate Hepatitis C Virus Research

The Discovery of Hepatitis C Virus Hepatitis, or the inflammation of the liver, is primarily caused by viral infection. Other significant factors to it include alcohol abuse, environmental contaminants, and autoimmune diseases. It became apparent in the 1940s that there were two major forms of contagious hepatitis. In the 1960s, Hepatitis B and A vaccines […]

DNA Microarray vs. High-Throughput Sequencing: A Brief View and the Applications in Gut Microbiome Research

With the advent of the post-genome era, gene chip and next-generation sequencing have become two important branches of biochemistry and molecular biology technologies. DNA microarray, also known as gene chip, is a method characterized by high throughput, high efficiency, and high automation. In a gene chip array, a large number of known probe sequences are […]

Applications of Single-Cell Sequencing Technology in Microbial Ecology

Microbial ecology is the study of the relationships of microorganisms with one another and with their environment. Microbial diversity, distribution, abundance, specific interactions, and their impact on ecosystems are explored. Elected by the scientific journal Nature as one of the technologies to watch for in 2020, single-cell sequencing is a rising technology in single-cell ecology. […]

Plasmid Fact Sheet: Definition, Structure and Application

What is a plasmid? Plasmids are the small circular or linear double-stranded DNA molecules (ranging from a few to several hundred kilobases) found in bacterial cells but also present naturally in archeae and eukaryotes. The plasmids are not packaged inside a chromosome, and have no distinct 5’ or 3’ beginning or end. They can autonomously […]

Microbial Genomics Approaches to Promote Crop Yield

The importance of microbiology in crop yield Plants, bacteria, and fungi have coexisted in soil in a symbiosis for millions of years, and they both benefit greatly from symbiosis. Healthy microbial communities perform a variety of vital ecosystem functions, such as pathogen suppression and regulation of nutrient availability. For example, microorganisms make essential elements such […]