CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Yearly Archives: 2018

Microbial Genomics Approaches to Promote Crop Yield

The importance of microbiology in crop yield Plants, bacteria, and fungi have coexisted in soil in a symbiosis for millions of years, and they both benefit greatly from symbiosis. Healthy microbial communities perform a variety of vital ecosystem functions, such as pathogen suppression and regulation of nutrient availability. For example, microorganisms make essential elements such […]

A Summary of Microbial Research in Animals

Why do we need to perform microbial research in animals? Enormous amounts of microorganisms live both within and on animal, the animal and its microorganisms exchange energy substances, transmit information to each other and form a holistic system. The impact of microorganisms on animal health is mainly reflected in mutual benefit sharing and symbiosis. If […]

Why Do We Perform 16S rRNA Sequencing

What is 16S rRNA? 16S ribosomal RNA (or 16S rRNA) is the component of the 30S small subunit of a prokaryotic ribosome, roughly 1500 base pairs. Figure 1A shows how 16S rRNA is involved in a prokaryotic ribosome. The bacterial 16S rRNA gene contains nine hypervariable regions (V1-V9) ranging from 30-100 base pairs, flanked by conserved regions (Figure 1C). You can find […]

18S rRNA and Its Use in Fungal Diversity Analysis

What is 18S rRNA? 18S ribosomal RNA (18S rRNA) is a component of the small eukaryotic ribosomal subunit (40S), and 40S and 60S constitute eukaryotic ribosomes. As a structural RNA for eukaryotic ribosomes, 18S rRNA, the homologue of 16S rRNA in prokaryotes and mitochondria, is thus one of the essential components of all eukaryotic cells. […]

Principle and Workflow of Illumina Next-generation Sequencing

Illumina, established in 1998 in San Diego, CA, is a leading company in the field of sequencing. In 2006, Illumina acquired Solexa, got the next-generation high-throughput sequencing technology and developed it into a mainstream technology on the market. It currently provides sequencing systems such as MiSeq, HiSeq 2500, HiSeq 3000, HiSeq 4000, HiSeq X Ten, HiSeq […]

Evolutionary Factors Have Stronger Influence on Gut Microbiome than Diet Patterns

As we all know that gut microbes provide multiple services to host, including digestion. Mammals with special diets, such as carnivores and anteaters, have special gut microorganisms to make it possible for them to eat such food. A common theme in the microbiome field is that the host diet has a significant impact on their […]

16S rRNA, One of the Most Important rRNAs

What is the 16S rRNA 16S rRNA (16S ribosomal RNA), is a component of the prokaryotic ribosome 30S subunit. The “S” in 16S is a sedimentation coefficient, that is, an index reflecting the downward velocity of the macromolecule in the centrifugal field. The higher the value, the greater the molecule. The 16S rRNA gene is […]

Basic Facts about Microsatellite Genotyping—Introduction to Microsatellites

Microsatellites, also known as simple tandem repeats (STRs), are simple repeat sequences distributing in eukaryotic genomes, which are composed of 2 ~ 6 nucleotide tandem repeats. The repeating times in individual are variable, therefore, the application of microsatellite markers is very extensive. Microsatellite loci is usually amplified by PCR. PCR products are analyzed by electrophoresis […]

Genomics—Forensic Age Identification

Summary: a DNA methylation age inference method, combined with Sequenom MassARRAY technology, can reduce the error of the age to 4.7 years. Age estimation is one of the most important topics in the field of forensic medicine. Especially for juvenile delinquency, highly corrupt bones of the dead and nameless corpse, it can provide the scope […]

Discovery of Susceptibility Gene ETV6 and Its Common Genetic Variants in the New Colorectal Cancer

Genome-wide association study (GWAS) is a kind of method to detect all or most of the genes among different individuals in specific species and to understand the genetic variation between different individuals. Many susceptibility genes and loci have been found in colorectal cancer using the GWAS method, but there are still many unknown susceptibility genes […]