Fungi are a kind of magical creatures. They are in various forms, from microscopic yeasts to mushrooms and fungus visible to the naked eye. It is not only different from the photosynthesis of plants, but also different from the feeding mode of animals. It survives by absorbing nutrients from the surrounding environment. Widely distributed in […]
Eubacteria belong to the prokaryotic domain, with prokaryotic cell structure, nuclear wrapped by nuclear membrane, and genetic material DNA exposed in the quasi-nuclear region. Binary fission is the main breeding mode, and some of them can form spores to resist adversity in harsh environment. Metabolic types are diverse, including photoautotrophic, chemoautotrophic, photoheterotrophic and chemoheterotrophic. Respiratory […]
Eubacteria, as an ancient and diverse microbial group on the earth, are widely distributed in every corner of our lives. From hot springs to cold polar regions, from fertile soil to deep oceans, there are traces of them. Although this kind of prokaryote is small, it occupies an irreplaceable key position in the operation of […]
In contemporary biological research, the handling of high-dimensional data has emerged as a significant challenge. For instance, in the analysis of microbial communities and gene expression data, samples often encompass thousands of features (such as Operational Taxonomic Units (OTUs) or gene expression values). Direct analysis of these high-dimensional datasets not only involves substantial computational effort […]
Organisms live in an ecological context, and pure cultures rarely exist in nature. Microbial communities comprising microecology are one example of systems that are far from being pure culture which makes them dynamic in playing roles in the ecosystem. Despite their abundance and ubiquity, our understanding of microecology, their interactions, and functions lag our knowledge […]
In recent years, studies have been progressively conducted to assess the effect of distinct sampling techniques on the outcomes of fecal microbiome assessment, in order to address this unmet need in the area of microbiome research. These methodology researches are useful for researchers to create quite rational guidelines for the procedure of fecal sampling, handling, […]
When bacteria, fungi, viruses, and parasites change over time and no longer respond to antibiotics, antimicrobial resistance (AMR) occurs. This makes an emerging issue related to the development and usage of antibiotics. Traditional microbial screening methods for AMR can be very laborious and time-consuming. However, the use of next-generation sequencing (NGS), especially whole-genome sequencing (WGS), […]
Without previous understanding of organisms, next-generation sequencing (NGS) offers an efficient unbiased approach to determine new coronavirus strains and other pathogens. New variants of the SARS-CoV-2 coronavirus are increasingly concerned about the rapid spread, highlighting the necessity for more sequencing to rapidly identify mutations and limit the risk of new strains. Sequencing was employed early […]
Clustered regularly interspaced short palindromic repeats, or CRISPR, is one of the most phenomenal discoveries that paved the way for modern genome screening and editing technologies. CRISPR is a family of DNA found in the genome of prokaryotes, specifically bacteria and archaea. These sequences contain DNA fragments from known bacteriophages that infect the particular prokaryote. […]
The Discovery of Hepatitis C Virus Hepatitis, or the inflammation of the liver, is primarily caused by viral infection. Other significant factors to it include alcohol abuse, environmental contaminants, and autoimmune diseases. It became apparent in the 1940s that there were two major forms of contagious hepatitis. In the 1960s, Hepatitis B and A vaccines […]
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