Genomics News

May 20, 2019

The Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a fundamental epigenomics approach and has been widely used in profiling the chromatin accessibility dynamics in multiple species. A comprehensive reference of ATAC-seq datasets for mammalian tissues......

May 16, 2019

Clean separation of cancer cells from a patient’s blood sample has been an ongoing challenge for the liquid biopsy field. The ability to perform molecular analysis on circulating tumor cells (CTCs) at single-cell resolution offers great promise to advance......

May 8, 2019

RNA-Seq is a whole-transcriptome analysis method used to research biological mechanisms and functions but its use in large-scale experiments is limited by its high cost and labour requirements. In this study, we have established a high-throughput and cost-effective RNA-Seq library preparation......

August 1, 2019

The genes that enable a fish to re-grow limbs have been found to be present in humans, new research has found. This insight could help develop regenerative treatments in humans. Many species can regenerate limbs after amputation including......

April 29, 2019

Arthropod silk is known as a versatile tool, and its variability makes it an attractive biomaterial. Eumeta variegata is a bagworm moth (Lepidoptera, Psychidae) that uses silk throughout all life stages. Notably, the bagworm-specific uses of silk include larval development in a bag coated......

April 19, 2019

Genome-wide gene expression analyses by RNA sequencing (RNA-seq) have quickly become a standard in molecular biology because of the widespread availability of high throughput sequencing technologies. Nonetheless, RNA sequencing is still expensive and time-consuming......

April 12, 2019

Recently, a new article entitled "Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas" was published in Molecular Cell journal, revealing a new gene editing tool which goes beyond the usual mechanisms of CRISPR......

April 5, 2019

A new Northwestern University study challenges prevailing understandings of genes that long-term poverty can be “embedded” across the genome. Previous research has shown that socioeconomic status (SES) is a powerful determinant of human health and disease, and social inequality......

March 25, 2019

A team of engineers at the UC Berkeley and the Keck Graduate Institute (KGI) of The Claremont colleges combined CRISPR with electronic transistors made from graphene to create a new hand-held device that can detect specific genetic mutations in a matter of minutes......

March 14, 2019

We previously used RNA-seq to identify chemicals whose effects on neuronal gene expression mimicked transcriptional signatures of autism, aging, and neurodegeneration. However, this approach was costly and time consuming, which limited our study to testing......

February 26, 2019

Rare diseases and their underlying molecular causes are often poorly studied, posing challenges for patient diagnosis and prognosis. The development of next-generation sequencing and its decreasing costs promises to alleviate such issues by supplying personal genomic information......

February 4, 2019

Oxford Nanopore has launched its two new ‘109’ cDNA Kits for its real-time, scalable sequencing technology. The new kits provide high throughput while generating complete sequences of full-length cDNA strands, with a low input option of just 1ng PolyA+ RNA.......