CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Monthly Archives: April 2024

What is The Role of RNA m6A Methylation

RNA modifications, notably N6-methyladenosine (m6A) methylation, have risen to prominence as pivotal orchestrators of gene expression and cellular dynamics. Within this array of modifications, the m6A methylation of RNA, especially within messenger RNA (mRNA) transcripts, has garnered considerable interest due to its profound involvement in diverse biological phenomena and the onset of pathological conditions. In […]

Introduce to 16S rRNA and 16S rRNA Sequencing

What Is 16S rRNA? The 16S rRNA (16S ribosomal RNA) is a constituent component of the 30S subunit in prokaryotic ribosomes. The “S” in 16S pertains to the Svedberg unit, a measure that reflects the sedimentation rate of large molecules in a centrifugal field – the higher the value, the larger the molecule. The 16S rRNA gene […]

Primer Walking Sequencing vs Shotgun Sequencing: A Comprehensive Comparison

In the field of genomics, two notable methodologies for DNA sequencing have risen to prominence: Primer Walking Sequencing and Shotgun Sequencing. These techniques, although distinct in their approaches, stand as indispensable instruments for deciphering the intricacies inherent within the genetic code. This discourse endeavors to dissect the nuances of both methodologies, elucidating their fundamental principles, […]

Exploring Small RNA: Types, Functions, Regulation, and Sequencing

The vital roles played by small RNA molecules in gene regulation and a myriad of cellular processes are undeniably essential within the realms of biological sciences. This extensive review encompasses a deep exploration into the complex nature of small RNA. We examine its definition, the diversity of its types, its multifaceted functions, as well as […]

Advancements in DNA Methylation Detection: From Bisulfite Treatment to Cutting-Edge Chip Technologies

1992 Bisulfite Treatment for Methylation Samples Commonly referred to as BS conversion, it involves treating methylated samples with bisulfite (abbreviated as "BS"), where "conversion" refers to the process by which unmethylated cytosines (C) are converted to uracils (U) and eventually to thymines (T) through PCR amplification, while methylated cytosines (5mC) are preserved. 2003 Pyrosequencing Pyrosequencing […]