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Role of Non-coding RNAs in Gene Regulation

Role of Non-coding RNAs in Gene Regulation

Non-coding RNA (ncRNA) is a type of RNA molecule that does not have the ability to encode proteins and plays a vital role in gene regulatory networks. In the past, people believed that the main function of RNA was to serve as a bridge for information transmission between DNA and protein, but with the deepening […]

Transcription in Eukaryotes vs. Prokaryotes: Initiation, Regulation, and Processing

Transcription in Eukaryotes vs. Prokaryotes: Initiation, Regulation, and Processing

In biology science, transcription is the core biological process of transforming DNA genetic information into RNA and is the key link of gene expression regulation. Although both eukaryotes and prokaryotes rely on transcription to realize the transmission and expression of genetic information, due to the significant differences in cell structure, metabolic needs, and survival strategies, […]

From Mechanism to Medicine: Understanding Eukaryotic Transcription Errors, Diseases and Treatments

From Mechanism to Medicine: Understanding Eukaryotic Transcription Errors, Diseases and Treatments

Eukaryotic transcription is a key initial step of gene expression, and its precise regulation is important for maintaining cell homeostasis and normal physiological functions of organisms. In recent years, more and more studies show that the disorder of the transcription process is closely related to the occurrence and development of many human diseases. An in-depth […]

Eukaryotic Transcription: Key Stages, Regulatory Mechanisms, Products, and Significance

Eukaryotic Transcription: Key Stages, Regulatory Mechanisms, Products, and Significance

Eukaryotic transcription is a key initial step of gene expression, which occupies a core position in the central rule. It uses DNA as a template to synthesize various RNA molecules by RNA polymerase. Its regulatory network is fine and complex, and it is widely involved in life activities such as embryonic development, cell differentiation, and […]

Reverse Transcription: An In-Depth Exploration of Structure, Function and Application

Reverse Transcription: An In-Depth Exploration of Structure, Function and Application

As a key phenomenon in the field of molecular biology, reverse transcription subverts the traditional "central rule" cognition and greatly expands people’s understanding of the law of genetic information transmission. This process refers to the process of synthesizing DNA with RNA as a template under the catalysis of reverse transcriptase, which breaks the one-way flow […]

Exploring cDNA: Introduction, Synthesis, gDNA Comparison, and Overcoming Challenges

Exploring cDNA: Introduction, Synthesis, gDNA Comparison, and Overcoming Challenges

In the field of modern biology science, the continuous innovation of molecular biology technology promotes the exploration of gene function and regulation mechanism. As a synthetic DNA sequence, complementary DNA (cDNA) originated from the reverse transcription process of messenger RNA (mRNA), and has played an indispensable core role in many frontier research fields such as […]

cDNA vs. gDNA: Structure, Function, Biotech Apps, and Why Choose cDNA

cDNA vs. gDNA: Structure, Function, Biotech Apps, and Why Choose cDNA

In the field of molecular biology, complementary DNA (cDNA) and genomic DNA (gDNA) are two crucial concepts, which play a key role in life science research, biotechnology application and many other aspects. Although both of them are related to the transmission and interpretation of genetic information, there are significant differences in structure, function and acquisition […]

cDNA: Current Applications and Future Horizons

cDNA: Current Applications and Future Horizons

In the deep exploration of contemporary molecular biology, complementary DNA (cDNA) has become the core factor to promote the development of multi-dimensional research with its excellent characteristics. With the deepening study of gene expression regulatory network, functional genomics framework and molecular pathological mechanism of diseases, the limitations of traditional research strategies in the face of […]

Mastering Plant RNA Extraction Methods, Steps, and Techniques for High-Quality Research

Mastering Plant RNA Extraction Methods, Steps, and Techniques for High-Quality Research

Plant RNA Extraction Overview In the extensive domain of molecular biology, the extraction of RNA from plants is recognized as a fundamental procedure in the study of gene expression, functional genomics, and transcriptomics. RNA,a conduit for genetic information, plays a pivotal role in various aspects of plant growth, development, and response to environmental stresses. However, […]

RNA Viruses: Insights into Their Classification, Replication Strategies and Advanced Extraction Protocols

RNA Viruses: Insights into Their Classification, Replication Strategies and Advanced Extraction Protocols

RNA virus belongs to the first class of virus classification, and its core feature is that the genetic material is RNA rather than DNA. This kind of virus widely exists in nature, including many pathogens that have great influence on human health, such as influenza virus, HIV, novel coronavirus (SARS-CoV-2) and so on. According to […]

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