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Million-Year-Old DNA Provides a Glimpse of Mammoth Evolution February 17/2021

February 17, 2021 In 2013, DNA from a horse that lived sometime between 560,000 and 780,000 years ago was sequenced. It was the most ancient DNA sample ever analysed. But that record has just been sma......

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Genome-Wide Detection of Cytosine Methylation by Single Molecule Real-Time Sequencing February 02/2021

Tse OYO, Jiang P, Cheng SH, Peng W, Shang H, Wong J, Chan SL, Poon LCY, Leung TY, Chan KCA, Chiu RWK, Lo YMD PNAS February 02, 2021 118 (5) e2019768118 Abstract 5-Methylcytosine (5mC) is an important ......

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DNA-Editing Method Shows Promise to Treat Mouse Model of Progeria January 06/2021

January 06, 2021 Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extre......

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Characterization of the Complete Chloroplast Genome Sequence of Dalbergia Species And Its Phylogenetic Implications December 31/2019

December 31, 2019 Yun Song, Yongjiang Zhang, Jin Xu, Weimin Li & MingFu Li Scientific Reports volume 9, Article number: 20401 (2019) Abstract The pantropical plant genus Dalbergia comprises approx......

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Top 10 Most-Read Genomics News Stories of 2019 December 20/2019

December 20, 2019 2019 was an exciting time for research developments in the genomics field. Here, we revisit the top 10 most-read news stories published on Front Line Genomics. New Blood Test Can Det......

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Autoimmune Issues Could be Linked to Extra X Chromosome in Females December 12/2019

December 12, 2019 Researchers have discovered a possible explanation for why autoimmune disease are more common in females. The research, Published in the Proceedings of the National Academy of Scienc......

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Trio Deep-sequencing Does Not Reveal Unexpected Off-target and On-target Mutations in Cas9-edited Rhesus Monkeys December 4/ 2019

December 4, 2019 Xin Luo, Yaoxi He, Chao Zhang, Xiechao He, Lanzhen Yan, Min Li, Ting Hu, Yan Hu, Jin Jiang, Xiaoyu Meng, Weizhi Ji, Xudong Zhao, Ping Zheng, Shuhua Xu & Bing Su Nature Communications ......

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Gut Microbiota Imbalance Promotes The Onset of Colorectal Cancer November 26/2019

November 26, 2019 Sporadic Colorectal Cancer is one of the most common cancers worldwide with over 42,000 cases a year in the UK and a 57% survival rate over ten years. The exact causes of colorectal ......

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The New Way to Translate A Dog’s Age into Human Years November 18/2019

November 18, 2019 Over 100,000 people die each day from age-related causes and the mechanisms are poorly understood. The main factors implicated are cell death, DNA damage and DNA methylation. Whether......

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Ultralow Amounts of DNA from Long-term Archived Serum Samples Produce Quality Genotypes November 12/2019

December 12, 2019 Trine B. Rounge, Marianne Lauritzen, Sten Even Erlandsen, Hilde Langseth, Oddgeir Lingaas Holmen & Randi E. Gislefoss European Journal of Human Genetics (2019) Sample characteristics......

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