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DNA Methylation Microarray Service

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CD genomics provides robust methylation profiling microarray service with extensive coverage of CpG islands, genes, and enhancers.

The Introduction to DNA Methylation Microarray

DNA methylation plays an important and dynamic role in regulating gene expression. DNA methylation is essential for normal development and is associated with a number of key processes including genomic imprinting, X-chromosome inactivation, suppression of repetitive elements, and carcinogenesis.

Utilizing the highly trusted, proven DNA analysis platforms in the industry, CD Genomics will assist you in the epigenome wide association studies, combining of the comprehensive, expert-selected coverage and high-throughput compatible with large sample size.

Table 1. Available DNA methylation microarray

Microarray

Species

Coverage

Platform

Infinium MethylationEPIC array

Human

Over 850,000 methylation sites per sample at single-nucleotide resolution

Illumina

Human CpG Island Microarray

Human

27,800 CpG islands covering 21 MB

Agilent

Human DNA Methylation Microarrays

Human

27,627 expanded CpG islands and 5081 UMR regions

Agilent

Mouse CpG Island Microarray

Mouse

15,342 CpG islands

Agilent

Features and Benefits

  • Personalized service with dedicated and collaborative experts
  • Reliable, proven, and rapid processes
  • Fully automated and integrated Laboratory Information Management System (LIMS)
  • Industry-leading data quality
  • Comprehensive study types

DNA methylation Microarray Workflow

This Agilent Methylation Assay protocol describes the use of methylation microarrays for the analysis of Methylated DNA Immunoprecipitation (MeDIP).

Agilent Methylation Assay workflowFig. 1 Agilent Methylation Assay workflow

The illumina Infinium Methylation Assay Protocol combines bisulfite conversion of genomic DNA and whole-genome amplification (WGA) with direct, array-based capture and scoring of the CpG loci.

Infinium methylation assay workflowFig. 2 Infinium methylation assay workflow

Our Full Service covers the complete process, from quality control of the samples to final data analysis. Besides, CD Genomics can also help create your own custom microarray which can be tailored to meet specific project requirements. If you have additional requirements or questions, please feel free to contact us.

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Email: info@cd-genomics.com