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Mycoplasma Detection


Mycoplasma exists widely in nature, and many kinds of mycoplasma can be pathogenic to humans, animals, plants and insects. Mycoplasma contamination has many effects including metabolism, biochemical characteristics, growth status, cell structure, etc. It directly affects the productive efficiency and product quality of research laboratories, regenerative medicine, biotechnological productions and biopharmaceutical industry. Besides, mycoplasma contamination is a major headache for cell culture. We provide mycoplasma detection to help you detect and quantitate mycoplasma in diverse samples.

Our Advantages:
  • Decades of experience in genomics service and proven expertise in microbial genomics.
  • High-resolution and high-reproducibility data.
  • Extensive experience in handling various samples.
  • Exquisite gel electropherogram.
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We are dedicated to providing outstanding customer service, listening to customer requests and being reachable at all times.

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Introduction to our mycoplasma detection solution

Mycoplasma, is a kind of microorganisms between bacteria and virus in taxonomy and is the smallest and simplest prokaryote found so far. Mycoplasma lacks cytoderm, and the only organelles visible in cells are ribosomes, making it resistant to antibiotics such as penicillin. Mycoplasma contamination of cell cultures is a widespread phenomenon in laboratories, ranging from 5 to 35% in published reports. It has severe impacts on cell proliferation and culture health, leading to wrong research results or unqualified biotechnology products. Therefore, mycoplasma detection is important for laboratory research, medical research, drug production, etc.

We identify mycoplasma based on MicroSEQ®, which combines the latest DNA sequencing technology and powerful analysis software, then obtains the identification result of mycoplasma by automatic sequencing of 16S rRNA gene, and finally obtains the identification result of mycoplasma by automatic sequencing of 16S rRNA gene. If required, real-time PCR can be used to quantitate mycoplasma. We are dedicated to delivering high-quality information about whether cell banks, raw materials, bulk and final drug products are polluted by mycoplasma. Mycoplasma detection is also used in medical research of mycoplasma infections. We can detect about 30 different mycoplasma species, such as M. fermentans, M. hyorhinis, M. pirum, M. hominis, M. argininii, M. pneumoniae, Acholeplasma laidlawii, etc.

Project Workflow

Bioinformatics Analysis

Service Analysis content
Mycoplasma Detection Determination on whether any mycoplasma is present in your sample
Mycoplasma Identification Detection of mycoplasma species and strains
Mycoplasma Quantitation Determination of mycoplasma abundance
Custom Analysis Other analysis based on your needs

Sample Requirement

Note: Our service is for mycoplasma detection only, and not for disease diagnostic procedures.

References

  1. Young L, Sung J, Stacey G, et al. Detection of Mycoplasma in cell cultures. Nature protocols, 2010, 5(5): 929.
  2. Olarerin-George A O, Hogenesch J B. Assessing the prevalence of mycoplasma contamination in cell culture via a survey of NCBI’s RNA-seq archive. Nucleic acids research, 2015, 43(5): 2535-2542.

Areas of Interest

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