Microbes was considered human’s enemies due to their ability to cause disease. However, it is now clear that they are good at synthesizing biologically active molecules and even used as therapeutics. Indeed, more and more pharmaceutical companies are now taking microbial therapeutics as the lead in clinical development. The potential of microbial therapeutics is evident in the probiotics and live bacterial prophylactic vaccines, as well as more recent cases that using fecal microbiota transplant to improve human health or cure certain diseases. Besides, microorganisms can be engineered to act as living therapeutics designed to perform specific functions in the human body, such as the prevention of infections, elimination of tumors, and treatment of metabolic disorders. Engineered living systems are considered as the next generation of therapeutics. The production and delivery of therapeutic drugs by microbes has several advantages over traditional systems: decreased production costs, side effects, and dosage requirements.Request a Quote
The microbiome has progressively become an attractive target for potential therapeutics. However, one of the biggest difficulties is to determine cause-effect relationships and to design microbial therapeutics for these conditions. We are dedicated to offering a full list of microbial genomics services to accelerate the development of microbial therapeutics, including microbial whole genome sequencing, 16S/18S/ITS sequencing, metagenomics, metatranscriptomics, microbial epigenomics, prokaryotic RNA sequencing, as well as microbial ID and AMR profiling.
Note: Our service is for research use only, not for disease diagnosis or treatment.
Bacteria, archeae, fungi, protozoan, viruses.
Next-generation sequencing (NGS), long-read sequencing, quantitative PCR (qPCR), and other molecular biology techniques.
Illumina HiSeq/MiSeq, Nanopore systems, PacBio RSII, PacBio Sequel, Applied Biosystems real-time PCR platforms, et al.
Figure 1. The high-throughput sequencing analysis process.
Our bioinformatics analysis pipeline is flexible to your needs.
|Taxonomic Assignment||Species annotation|
|Rank Abundance Curve|
|Principal Components Analysis (PCA)|
|Functional analysis||BLASTX, KEGG, eggNOG, CAZy, CARD, ARDB etc.|
|Phylogenetic Analysis||(Un)Weighted Unifrac|