Shallow Shotgun Metagenome Sequencing

Shallow shotgun metagenome sequencing (SSMS) requires sample sequencing at a shallower depth than is performed in complete shotgun sequencing. Shallow shotgun sequencing, without the need for traditional deep sequencing, will profile up to 0.05 percent of a microbial population. SSMS provides a smaller representation of the microbial community and higher taxonomic resolution than amplicon sequencing by combining more samples into a single sequencing run and using a modified protocol that uses fewer reagents for sequencing library preparation. SSMS is an economical way to provide a smaller representation of the microbial community and higher taxonomic resolution than amplicon sequencing; SSMS provides composition and function similar (but still not a substitute) to deep-shotgun genome sequencing sequencing data.

Scientists at CD Genomics can access the microbiome with higher species level resolution than 16S sequencing with Shallow Shotgun Sequencing, while still retaining price, making it a perfect alternative for large cohort studies focused on the various microbiomes. We provide you with routine testing, precise functional profiles, reliable taxonomic resolution, and large-scale human microbiome studies.