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Introduction of Some Newly Launched Sequencers (3)

— Ion S5/S5 XL is the latest NGS system from Thermo Fisher Scientific

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December 4, 2018

The Ion S5/S5 XL next-generation sequencing system enables a simple targeted sequencing workflow for your lab at an affordable price, with reliable performance and industry-leading speed. The Ion S5/S5 XL System leverages the speed of semiconductor sequencing with impressive on-board computing power, to enable the production of high quality sequencing data in as little as 2.5 hours and enable you to go from DNA library to data in as little as 24 hours with only 45 minutes of total hands-on time on the Ion Chef™ System and the Ion S5/S5 XL System. The Ion S5/S5 XL System is simple to use with cartridge-based reagents and offers superior scalability and flexibility to support a broad range of high throughput sequencing applications, from microbial genomes and gene panels to exomes and transcriptomes.

Speed
With the Ion S5/S5 XL System you get results in as little as 24 hours (with a 2.5-4 hour sequencer run time and overnight Ion Chef System run)—the fastest turnaround of any next-generation sequencer currently on the market.

Ion S5/S5 XL is the latest NGS system from Thermo Fisher Scientific* Expected output with >99% aligned or measured accuracy. Output dependent on read length and application.
** Analysis time to aligned BAM files.
† Ion 510 Chip is only compatible with the Ion Chef System workflow for template preparation. The Ion 510 Chip is not enabled for the Ion OneTouch™ 2 System template preparation workflow.
†† 600 bp sequencing is not enabled for Ion 510 Chip and Ion 540 Chip.

Simplicity
With single-day installation, a straightforward user interface, and cartridge-loaded reagents, the Ion S5/S5 XL System is easy to use. Beyond this, the system is part of a workflow that allows you to go from DNA to data with only 45 minutes of total hands-on time on the Ion Chef System and the Ion S5/S5 XL System. Combined with Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation, targeted sequencing becomes simpler than ever.

Small sample input
Low input DNA for challenging samples types, such as formalin-fixed paraffin-embedded (FFPE) tissue, retrospective samples from fine needle aspirates, and cell-free DNA extracted from blood (cfDNA). With Ion AmpliSeq technology and the Ion S5/S5 XL Sequencer, you can use as little as 10 ng input DNA or RNA.

Scalability
Why buy multiple systems for your lab when you can run all your targeted sequencing or microbial research applications on a single next-generation sequencer? The Ion S5 XL System has a modular build, so your lab has the flexibility to do multiple targeted sequencing applications on a single system.

Simple analysis and storage solutions
Whether you are new to next-generation sequencing or an expert user, Torrent Suite™ Software and Ion Reporter™ Software make it easy for you to get started with next-generation sequencing. Plan, monitor, track, and analyze your runs using Torrent Suite Software (pre-installed on the Torrent Server). Integrate, annotate, and interpret variants using Ion Reporter Software (Cloud or local options available based on your needs).

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