The CDAmp™ BRCA1/2 Panel Kit is a multiplex PCR-based targeted resequencing assay designed to streamline the evaluation of germline and somatic variants across exon regions of BRCA1/2 genes and critical non-exonic ClinVar-annotated loci. This panel enables sensitive detection of point mutations and insertion-deletion (indel) variants, supporting research, genomic analysis, molecular characterization, and risk assessment for hereditary breast cancer, ovarian cancer, and related conditions.
Fast, Streamlined Workflow
· Generate sequencing-ready libraries in just 2hours using a rapid, two-step PCR protocol with minimal hands-on time.
Sensitive Detection
· Detect somatic mutations as low as 1% variant allele frequency.
Comprehensive Coverage
· Target all exonic regions and flanking intronic sequences to ensure high detection rates.
| Enrichment Method: | Multiplex PCR Amplification |
| Species: | Human |
| Variant Types: | SNV、Indel |
| Target Size: | 20.2Kb |
| Cancer Type: | Breast/Ovarian/Pancreas/Prostate Cancer |
| Number of Genes: | 2 |
| Sample Type: | Tissue、FFPE、Blood、Buccal Swab |
| Input DNA/RNA: | >30ng |
| Method: | NGS |
| Sequencing Platform: | Illumina |
| Storage: | Store at -20 °C. |
| BRCA1 | BRCA2 |
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