Rapid and accurate retrieval of whole genome sequences of human pathogens from disease vectors or animal reservoirs will enable fine-resolution studies of pathogen epidemiological and evolutionary dynamics. However, next generation sequencing technologies have not yet been fully harnessed for the study of vector-borne and zoonotic pathogens, due to the difficulty of obtaining high-quality pathogen sequence data directly with a high ratio of host to pathogen DNA.
Based on targeted NGS (tNGS) technology, Our Pathogen Targeted NGS Sequencing Services harnesses the power of cutting-edge sequencing technologies to address these challenges. This sophisticated technique enriches dozens to hundreds of known pathogenic microorganisms, along with their virulence and resistance genes, using ultra-multiplex PCR amplification or hybridization capture technology. Subsequently, high-throughput multi-pathogen parallel testing, grounded in NGS, is performed.
CD Genomics tNGS Technology
We provide customized bioinformatics analysis including:
CD Genomics provides the accurate and cost-effective pathogens capture sequencing and bioinformatics analysis. Our professional expert team executes quality management, following every procedure to ensure confident and unbiased results. The general workflow for pathogens capture sequencing panel is outlined below.
For more information about the pathogens capture or need other amplification requirements, please contact us.
CD Genomics Multiple Pathogen Targeted NGS service offers a cutting-edge solution for accurate identification of a wide range of microorganisms commonly found in the bloodstream, respiratory, and nervous systems. This comprehensive approach allows for the simultaneous detection of 219 pathogens, including elusive ones such as Mycobacterium avium, Nocardia, and Chlamydia psittaci, along with common drug resistance genes. Our service is characterized by exceptional clinical coverage, heightened sensitivity, unparalleled specificity, and the capability for precise typing. By swiftly targeting pathogens and providing crucial drug resistance information, our service stands at the forefront of diagnostic innovation.
Our Mycobacterium Targeted Sequencing Program is tailored to meet the specific challenges posed by Mycobacterium species. The program encompasses the forward enrichment and sequencing of target genes. This precision-driven initiative allows for accurate typing and classification, supported by concurrent testing of drug-resistant genes/subtypes. The outcome is a molecular diagnostic foundation for informed decisions.
Please refer to our Respiratory Pathogen NGS Panels, for more information about the Bacteria Targets of our tNGS products.