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CDAmp™ Human BCR Research Assay

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PNI003-1 24rxn
PNI003-2 96rxn
Overview

Product Description

CDAmp™ Human BCR Panel for comprehensive analysis of B-cell receptor (BCR) diversity via multiplex amplicon-based target enrichment for Next Generation Sequencing (NGS)It developed based on the proven CDAmp multiplex amplicon technology and cover V/D/J genes within the Complementarity-Determining Region 3 (CDR3) of BCR immunoglobulin heavy (IgH), kappa (Igκ), and lambda (Igλ) chains.

It offers a more sensitive, complete, and streamlined approach to understand the status of the immune repertoire. These panels can be used in tumor immune mechanism research, discovery of autoimmune disease markers, MRD marker tracking, antibody research and development, as well as immunogenic response assessment.

Features

Key Features & Advantages

Proven multiplex amplicon Technology
· Ensures excellent performance with robust and reliable multiplex amplification.
Comprehensive CDR3 Coverage
· Primers specifically designed for both ends of the V and J regions enable amplification of CDR3 regions for comprehensive immune repertoire profiling.
Balanced Amplification
· Utilizes advanced multiplex PCR techniques to achieve equivalent amplification of diverse clones, ensuring accurate representation of repertoire diversity.
Species Flexibility
· Panels are currently available for human samples and are open to customization for research involving other species.

Specifications

Product Specifications

Enrichment Method: Multiplex PCR Amplification
Species: Human
Sample Type: Blood、Tissue etc.
Input DNA/RNA: RNA> 10ng
Method: NGS
Sequencing Platform: Illumina
* For research purposes only, not intended for clinical diagnosis, treatment, or individual health assessments.
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