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Immune Repertoire Analysis Panel

Immune Repertoire Analysis Panel

Brief Introduction

T cells and B cells are the two major cell populations of the adaptive immune system, which are key measures of immune complexity. The study of immune repertoire is essential to understanding the immune profile. It ultimately reveals the discovery of new infection factors and potentially aids the development of antibodies/vaccines, clinical diagnosis, treatment, and prevention.

We have created human immune library sequencing products and services that characterize RNA input. Input from RNA can unbiasedly capture the phenotype of cell subpopulations. Our kits rely on multiplex PCR technology to simultaneously perform rapid, efficient, and accurate parallel analysis of large numbers of TCRs/BCRs, adapted for the measurement of complex samples and discovery of rare mutations.

Our Immune Repertoire Analysis Solution also can be applied to both solid tumors and blood cancers, including prognostic and genealogical analysis. It can be used to analyze tumor-infiltrating lymphocytes and compare TCR diversity. The diversity of Immune can predict prognosis and can be used to map neoantigens derived from cancer cells to the corresponding TCRs.

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Features of Our Immune Repertoire Analysis Panel

Applications of Our Immune Repertoire Analysis Panel

Product Specifications

Service Specifications Sample Requirements
  • Recommended amount: 20 ng for high-quality RNA samples; at least 400 ng RNA for fresh frozen tissue or PBMC samples
  • Minimum amount: 20 ng
Service Specifications Sequencing
  • Illumina MiSeq / NextSeq
  • Recommended sequencing depth: ≥100x
Service Specifications Bioinformatics Analysis
  • Raw data analysis and QC
  • Data filtering and alignment
  • Clustering analysis
  • Custom data analysis

Immune Repertoire Analysis Panel Workflow

Our Immune Repertoire Analysis products mainly apply unbiased gene amplification technology (multiplex PCR and molecular barcodes) to achieve comprehensive, high-precision repertoire analysis. Target enrichment and library preparation can be accomplished in a short period of time and are suitable for most Illumina sequencing platforms.

We offer not only products, but also complete sequencing and data analysis capabilities for a wide range of T cell receptor (TCR)/B cell receptor (BCR) repertoire analysis projects.

Gene Panel Workflow

* For research purposes only, not intended for clinical diagnosis, treatment, or individual health assessments.
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