Microsatellite instability (MSI) refers to the occurrence of errors or changes in the length of repetitive DNA sequences during DNA replication. Microsatellites are DNA regions that contain short, repetitive nucleotide sequences that can usually be accurately replicated and stably passed on. However, the replication machinery can go wrong, resulting in an abnormal number of repeats in the microsatellite sequence in MSI. MSI is commonly observed in tumors with defective mismatch repair (MMR) systems, such as colorectal, endometrial, gastric, ovarian, and pancreatic cancers. Recently, MSI testing has gained particular interest in cancer research and treatment to help guide treatment decisions. MSI testing can be accomplished by a variety of methods, including PCR-based assays and next-generation sequencing (NGS).
CD Genomics offers a wide range of MSI reference products to help you analyze MSI as a potential tumor biomarker to predict the efficacy of immunotherapy.
MSI assays are currently used as diagnostic tools to identify patients with Lynch syndrome or to help predict which tumors are likely to respond to immunotherapy. We offer 35 MSI reference products for innovative MSI assays or quality control of the corresponding kits.
Our MSI reference products are derived from cell lines that mimic patient samples.
Explore Our Microsatellite Instability (MSI) Reference Products:
| Cat. No. | Product Name | Brief Description | Inquiry | Basket |
|---|---|---|---|---|
| MSIR001 | CD MSI-H Reference-MSIR001 | CD MSI-H Reference-MSIR001 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR002 | CD MSI-H Reference-MSIR002 | CD MSI-H Reference-MSIR002 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR003 | CD MSI-H Reference-MSIR003 | CD MSI-H Reference-MSIR003 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR004 | CD MSI-H Reference-MSIR004 | CD MSI-H Reference-MSIR004 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR005 | CD MSI-H Reference-MSIR005 | CD MSI-H Reference-MSIR005 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR006 | CD MSI-L Reference-MSIR006 | CD MSI-L Reference-MSIR006 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR007 | CD MSI-L Reference-MSIR007 | CD MSI-L Reference-MSIR007 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR008 | CD MSI-L Reference-MSIR008 | CD MSI-L Reference-MSIR008 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR009 | CD MSI-L Reference-MSIR009 | CD MSI-L Reference-MSIR009 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. | ||
| MSIR010 | CD MSS Reference-MSIR010 | CD MSS Reference-MSIR010 is derived from a single sample of cell line and the MSI value corresponding to the sample is detected by capillary electrophoresis. |
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