The CDCap™ Lung Cancer Panel Kit is a hybridization capture-based targeted resequencing assay designed for clinical research and personalized treatment support in non-small cell lung cancer (NSCLC). This panel targets the full exon regions of 23 genes explicitly recommended in the NCCN Guidelines along with key hotspot fusion regions associated with BRAF, ALK, RET, ROS1, and MET Exon 14 Skipping Mutation. It enables comprehensive detection of somatic mutations, including SNVs, indels, fusions, and CNVs. The kit is optimized for low-input samples (e.g., ctDNA) and compatible with DNA extracted from FFPE, whole blood, tissue, and other clinical sample types.
Comprehensive Coverage
· Targets full exon regions of 23 NSCLC-associated genes and critical fusion regions to ensure detection of key variants.
Multi-Dimensional Detection
· Simultaneously identifies SNVs, indels, CNVs, and fusions to address diverse clinical needs.
Guideline-Driven Design
· Covers driver genes with established targeted therapies or clinical trial support as recommended by the NCCN Guidelines.
Broad Sample Compatibility
· Compatible with low-input samples (e.g., ctDNA) and supports DNA from FFPE, whole blood, tissue, and other sources.
| Enrichment Method: | Probe Hybridization Capture |
| Species: | Human |
| Variant Types: | SNV, Indel, Fusion, CNV |
| Target Size: | 170Kb |
| Cancer Type: | Lung Cancer |
| Number of Genes: | 23 |
| Sample Type: | Tissue、FFPE、blood |
| Input DNA/RNA: | cfDNA ≥20ng, gDNA ≥30ng |
| Method: | NGS |
| Sequencing Platform: | Illumina |
| Storage: | Store at -20 °C. |
| ALK* | BRAF* | CDKN2A | EGFR* | ERBB2 |
| KRAS | MAP2K1 | MET* | NRAS | PIK3CA |
| RET* | ROS1* | TP53 | NTRK1* | NTRK2* |
| NTRK3 | NF1 | STK11 | PTEN | FGFR1* |
| FGFR2* | FGFR3* | NRG1 |
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