The CDAmp™ Colorectal/Gastric Cancer Panel is a multiplex PCR-based targeted resequencing assay designed to interrogate 35 genes associated with colorectal cancer,gastric cancer, gastrointestinal stromal tumors (GIST), comprehensively covering genes explicitly recommended in the NCCN Guidelines for colorectal/gastric cancer and GIST . It enables tumor genetic risk assessment in healthy individuals and molecular subtyping for cancer patient samples to facilitate research analysis.
Clinically Relevant Gene Content
· Targets driver genes with established targeted therapies or clinical trial support as recommended by the NCCN Guidelines.
Fast, Streamlined Workflow
· Generate sequencing-ready libraries in just one day using a rapid, two-step PCR protocol with minimal hands-on time (2 hours).
Superb Performance
· Detect low-frequency mutations down to 1% variant allele frequency without requiring Unique Molecular Identifiers (UMIs).
| Enrichment Method: | Multiplex PCR Amplification |
| Species: | Human |
| Variant Types: | SNV, Indel, CNV |
| Target Size: | 85.9Kb |
| Amplicon Length: | 150 bp (110–205 bp) |
| Cancer Type: | Colorectal Cancer、Gastric Cancer、GIST |
| Number of Genes: | 36 |
| Sample Type: | Tissue、FFPE、blood |
| Input DNA/RNA: | 20–80 ng |
| Method: | NGS |
| Sequencing Platform: | IlluminaI; Ion Torrent |
| Storage: | Store at -20 °C. |
1. Excellent Capture Performance：Highly Efficient Capture and Uniform Coverage
| APC | DPYD | MSH2 | PIK3CA | SDHD |
| BMPR1A | EPCAM | MSH6 | PMS2 | SEMA3C |
| BRAF | ERCC1 | MUTYH | POLD1 | SMAD4 |
| C8orf34 | GREM1 | NQO1 | POLE | STK11 |
| CDH1 | KIT | NRAS | PTEN | TP53 |
| CTNNB1 | KRAS | NTHL1 | SDHB | TYMS |
| CYP19A1 | MLH1 | PDGFRA | SDHC | UGT1A1 |
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