CD Tumor Structure Variant 5% FFPE Standard

Key Features & Advantages

Quality Standards
(1)Fusion gene DNA mutation frequency is tesed by Droplet Digital PCR, the acceptance criteria as follows：
AF=0%, acceptable range ≤0.1%
0＜AF＜1%, acceptable error range = ±40%
1% ≤ AF <5%, acceptable error range = ±30%
5% ≤ AF ≤ 20%, acceptable margin of error = ± 20%
Copy number variation <5, acceptable error range = ±40%
5 ≤ copy number variation <10, acceptable error range = ±30%
Copy number variation ≥10, acceptable error range = ±20%
(2)Fusion gene RNA expression is tesed by End-Point RT-PCR.

SNV: AKT1 E17K, PIK3CA E545K.
Insertion: EGFR_A767_V769dup.
Deletion: EGFR ΔE746_A750.
Fusion: CD74(6)-ROS1(34),EML4(6)-ALK(20).
CNV: MET Amplification,ERBB2 Amplification.

Product Specifications