Comprising 16,569 base pairs in a double-stranded circular conformation, the human mitochondrial genome harbors 37 protein- and RNA-coding genes. This maternally inherited, multi-copy genome exhibits pronounced sequence heterogeneity and elevated mutation rates, correlating with diverse pathologies including degenerative conditions, metabolic syndromes, heritable disorders, and oncogenesis. CD Genomics delivers two comprehensive mtDNA analysis platforms: the CDCap™ Human Whole mtDNA Genome Panel Kit for hybridization capture-based workflows and the CDAmp™ Human Whole mtDNA Genome Panel Kit employing multiplex amplicon technology. The CDCap™ system further functions as a modular spike-in component for bespoke hybrid capture panel designs.
Full-Length Coverage
· Complete coverage of the entire 16,569 bp human mtDNA genome
Two Flexible Solutions
· The CDCap™ Human Whole mtDNA Genome Panel can also function as a spike-in module for customized hybridization capture panels, while the CDAmp™ Human Whole mtDNA Genome Panel enables rapid, easy, and cost-efficient library preparation workflows.
| Enrichment Method: | Probe Hybridization Capture/Multiplex PCR Amplification |
| Species: | Human |
| Target Size: | 67.1Kb |
| Sample Type: | blood、swab etc. |
| Method: | NGS |
| Sequencing Platform: | Illumina |
| Storage: | Store at -20 °C. |
1. Excellent Performance
Both approaches deliver robust performance with high-depth data output, full-length coverage of the mitochondrial genome, exceptional capture efficiency, and superior uniformity.
| 13 Protein - coding Genes | MT - ND1、MT - ND2、MT - ND3、MT - ND4、MT - ND4L、MT - ND5、MT - ND6、MT - CYB、MT - CO1、MT - CO2、MT - CO3、MT - ATP6、MT - ATP8 |
| 22 tRNA - coding Genes | MT - TA、MT - TR、MT - TN、MT - TD、MT - TC、MT - TE、MT - TQ、MT - TG、MT - TH、MT - TI、MT - TL1、MT - TL2、MT - TK、MT - TM、MT - TF、MT - TP、MT - TS1、MT - TS2、MT - TT、MT - TW、MT - TY、MT - TV |
| 2 rRNA - coding Genes | MT - RNR1、MT - RNR2 |
| 1 Regulatory Region | D - loop Region |
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