CDAmp™ Glioma Panel Kit utilizes the patented CDAmp technology to detect hotspot mutations in IDH1/2, TERTp, and BRAF genes, as well as in chromosomal regions 1p, 19q, and 10q for identification of large fragment deletions in glioma research. It facilitates molecular subtyping to support research analysis, investigational applications, and research on prognosis prediction.
Clinically Relevant Targets
· Detects IDH1/2, TERT, BRAF, and 1p19q co-deletion based on WHO and NCCN guidelines to enable disease subtyping.
Fast, Streamlined Workflow
· Generates sequencing-ready libraries in just 5 hours with less than 2 hours hands-on time.
Low Input Requirement
· Requires only 20 ng of input DNA to prepare libraries with sufficient concentration and yield for sequencing.
| Enrichment Method: | Multiplex PCR Amplification |
| Species: | Human |
| Variant Types: | SNV, Indel, CNV |
| Target Size: | 25.5 Kb |
| Amplicon Length: | ~153bp |
| Cancer Type: | Glioma |
| Number of Genes: | 13 |
| Sample Type: | Tissue; cerebrospinal fluid (CSF) |
| Input DNA/RNA: | 2.5~60 ng(recommend 20ng) |
| Method: | NGS |
| Sequencing Platform: | IlluminaI; Ion Torrent |
| Storage: | Store at -20 °C. |
| ATRX | BRAF | CDKN2A | CDKN2B | EGFR | H3F3A | HISTH3B |
| IDH1 | IDH2 | PIK3CA | PTEN | TERT | TP53 | 1p19q |
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