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info@cd-genomics.com
info@cd-genomics.com
The CDCap™ Solid Tumor HotSpot Panel is a hybridization capture-based targeted sequencing assay designed to interrogate "hotspot" regions of tumor-associated mutations across 49 genes implicated in carcinogenesis and tumor suppression, with probes covering approximately 25 Kb of the genome. This panel is optimized for use with the Optimized Capture System, leveraging its novel targeted enrichment technology to deliver enhanced capture efficiency, consistent performance, and reduced experimental time, enabling cost-effective and high-throughput sequencing workflows.
Multi-Dimensional Variant Detection
Simultaneously identifies SNVs, Indels, CNVs, and Fusions to support comprehensive clinical analysis.
Broad Cancer Type Coverage
Targets driver genes and hotspot mutation regions across nearly all common solid tumor types, facilitating informed precision therapy decisions.
High Sample Compatibility
Compatible with diverse sample types, including FFPE tissues, fresh tissues, and plasma cfDNA, and adaptable to major high-throughput sequencing platforms such as Illumina® systems.
| Enrichment Method: | Probe Hybridization Capture |
| Species: | Human |
| Variant Types: | SNV、Indel、Fusion、CNV |
| Target Size: | 25Kb |
| Probe Count: | 210+ |
| Cancer Type: | Pan-Cancer |
| Number of Genes: | 49 |
| Sample Type: | Tissue、FFPE、blood |
| Input DNA/RNA: | cfDNA ≥20ng, gDNA ≥30ng |
| Method: | NGS |
| Sequencing Platform: | Illumina/MGI |
| Storage: | Store at -20 °C. |
1. Excellent Capture Performance：Highly Efficient Capture and Uniform Coverage
2. Variant Analysis：Highly Accurate Mutation Detection
| AKT1 | ALK | APC | AR | ARAF | ATM | BRAF | CDKN2A | CHEK2 | CTNNB1 |
| DDR2 | EGFR | ERBB2 | ERBB3 | ESR1 | FBXW7 | FGFR1 | FGFR2 | FGFR3 | FGFR4 |
| FLT3 | GNA11 | GNAQ | GNAS | HRAS | IDH1 | IDH2 | KIT | KRAS | MAP2K1 |
| MAP2K2 | MET | mTOR | NRAS | NTRK1 | NTRK3 | PDGFRA | PIK3CA | PTCH1 | PTEN |
| RAF1 | RET | ROS1 | SF3B1 | SMAD4 | SMO | STK11 | TP53 | TSC1 |
Please submit a detailed description of your project. We will provide you with a customized project plan to meet your research requests. You can also send emails directly to info@cd-genomics.com for inquiries.
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