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HLA genes are a major contributor to drug hypersensitivity involving direct stimulation of immune effector cells and imitating an allergic. HLA-B*58:01 genotyping can be used to identify patients who are at increased risk for developing severe cutaneous adverse reactions (SCAR) after treatment with allopurinol, based on the presence of the HLA-B*58:01 allele. The kit is based on real-time PCR technology to detect human HLA-B*5801 gene in peripheral blood samples.
Target Gene: Human HLA-B*5801 Gene
Sensitivity: 1 ng/μL
Precision: ≤5%
Product Features:
• High Sensitivity -The limit of detection is up to 1 ng/μL
• Internal Control -The use of internal control system in the kit can effectively prevent false negative results
• High Precision -The precision values of intra and inter Ct values are all ≤ 5%
• User-friendly -Widely applicable in instruments with FAM, HEX/VIC, Cy5 fluorescence channels
• More Accessible -CE marked, accessible for more countries
Species: | Human HLA-B 5801 Drug Hypersensitivity |
Sample Type: | Peripheral blood |
Storage: | The kit is stored at -25℃~-15℃ for 12 months. |
Method: | Real-time PCR |
Equipment Required: | • Instruments with FAM, HEX/VIC • Cy5 fluorescence channels such as Applied Biosystems™ 7500 Real-time PCR Systems • Real-time PCR Systems |
ShippingCondition: | Dry ice |
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