The ubiquitous transcription of genomes generates large amounts of non-coding RNAs. Long non-coding RNAs (lncRNAs) are usually defined as transcripts that are more than 200 nucleotides in length and do not have any protein-coding potential. Computational methods have identified a large number of lncRNAs in different plant species. LncRNAs perform their functions by interacting with DNA, RNA, and protein molecules and regulating the expression levels of their targets through epigenetic, transcriptional, post-transcriptional, or translational regulation. With advances in next-generation sequencing (NGS) technologies, it has been discovered that a large number of lncRNAs in plants are involved in a wide range of biological processes, including regulation of flowering time and reproductive organ morphogenesis, abiotic and biotic stress responses, leaf development, growth hormone signaling, and photomorphogenesis.

Fig. 1. Verified functions of lncRNAs in rice. (Caixia et al., 2020)

Our long non-coding RNA (lncRNA) identification and characterization solution

Long non-coding RNAs (lncRNAs) play a critical role in plant development. However, information on lncRNAs in most plant species remains largely unexplored. CD Genomics provides whole genome analysis of lncRNAs in a variety of crops, including maize, rice, castor bean, rapeseed, Cajanus cajan (pigeon pea), Jatropha curcus, and Paeonia suffruticosa ( tree peony), etc. Our NGS high-throughput sequencing technology and transcriptome (RNA-seq) analysis can identify more lncRNAs in crops. In addition, our sequencing and bioinformatics approaches allow us to functionally annotate the targets of differentially expressed lncRNAs to examine their possible roles in plant development.

LncRNA for Molecular breeding

Many lncRNAs can regulate important agronomic traits in crops, and we are committed to identifying important lncRNA breeding targets and applying them in crop cultivation and breeding to improve crop quality and performance. Our services are designed to help you systematically study lncRNAs in plant development and analyze the function and developmental regulation of plant lncRNAs.

• Screening and characterization of lncRNAs.
• Analyze the expression patterns of lncRNAs at different stages of plant development.
• Characterize lncRNA functions, including target gene regulators, miRNA precursors, and miRNA targets.

LncRNA identification and characterization service process

Fig. 2. CD Genomics' lncRNA identification and characterization service process.

Our strengths and features

• Cutting-edge technology. Our state-of-the-art sequencing platforms and bioinformatics pipelines provide researchers with a competitive edge in lncRNA discovery, ensuring that our solutions are robust, reliable, and accurate.
• Expertise and experience. We have a team of highly experienced experts. Our researchers and bioinformaticians are well-versed in the complexities of lncRNA research, ensuring the success of your project.
• Customized solutions. We offer customizable solutions to meet the specific needs of your research or breeding program. Whether you are studying lncRNA in a model organism or an economically important crop, we will customize our services accordingly.

CD Genomics offers NGS and RNA-seq technologies to identify and characterize lncRNAs in plant species. We help you analyze lncRNA candidates and lncRNA-mediated regulatory networks that govern plant development and related agronomic traits. If you are interested, please feel free to contact us.

Reference

1. Caixia, Gao, et al. "Roles of lncRNAs in rice: advances and challenges." Rice Science. 27.5 (2020): 384-395.

Related Services
Animal and Plant Whole Genome Sequencing
Agricultural NGS Services
Transcriptome (RNA-seq) Services
Bioinformatics Analysis Services