CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Blog Archives

The Basic Information About SNP Genotyping of CD Genomics

What is SNP? SNP is the abbreviation of a single nucleotide polymorphism. It is the DNA sequence polymorphism caused by variation of single nucleotide, including the transition, transversion, insertion and deficiency of a single base. On average, one in 1,000 nucleotides in human genome is SNP. There are more than three million SNPs in the […]

The Application of Exome Sequencing in Disease Research

Exon is a part of eukaryotic genome sequence. The exome is the total of all exons, which takes one percent in the whole genome sequence of human beings. The exome sequencing is to capture and enrich the exome in the whole genome sequence by targeted capture, and get the genomic information by next generation sequencing. […]

Aging Related Gene Expressions

As human beings, we are all faced with the process of growing up, getting old and going to heaven. It’s a natural process that follows the rule of nature. But as human beings, this naturally comes to us that we are fearful of this process. We dream about immortality, which is reflected in many art […]

Nobel Prize for Chemistry 2015: DNA Repair is the High Light

After Youyou Tu won the Nobel Prize in Physiology or Medicine, thousands of people focus on the chemistry prize. Who will take this honor? Early the morning of Wednesday, the Royal Swedish Academy of Sciences announced the 2015 Nobel Prize went for three scientists: Tomas Lindahl, Paul Modrich and Aziz Sancar. They won this prize […]

Interesting Genetics: “Genetically Modified”Butterflies

With the development of genetic technology, you are no stranger to transgenic animals. But here I’m not talking about the gene editing technology of human beings, I’m taking about the “gene editing” of nature. You may be confused because it seems like the word “ gene editing” is something patent of human beings. We are […]

A Brief Introduction on DNA Methylation and Methods of Detection

Except DNA and RNA, there are many messages which will affect the gene expression in genome. They do not change the sequence, but have the power of regulation on function and characteristics of gene by chemical modification, RNA interference and the interaction between protein and DNA. This change will be passed to the next generation. […]

Improvement of Nanopore Sequencing: The Accuracy Was Greatly Improved

As a new technology of sequencing, the biggest advantage of nanopore is its low cost. Compared to other sequencing technology, such as sanger sequencing and next generation sequencing, the nanopore sequencing does not need any fluorescein for purification, and the process of DNA amplification is also unnecessary. It can save both money and time. Besides, […]

The Biggest Amount of Whole Genome Sequence Data Was Published

Recently, the research about the whole genome sequencing of the biggest population was published in Nature. It described the source and the application of the data. The rare variant is the transformation carried in DNA. It is not common, but important to many diseases. To find out the relationship between rare variants and disease and […]

New Discovery about CRISPR: Treatment of SCD

Recently, researchers form Dana-Farber found that a small change of DNA can avoid some genetic defects of SCD, this research was published on nature on September 16. Sickle cell disease is a kind of genetic disease, which is caused by the mutation of hemoglobin. This disease is common in Africa, and also takes place in […]

Metagenomics Class:Metagenomics And Related Research

The concept of metagenome was proposed by Handelsman in 1998. It is the sum of DNA in a specific circumstance. Metagenomics is the research about the genome of micropopulation in the circumstance. It studies the microbial diversity, microbial population, evolutionary relationship, and its relationship with circumstance by structure functional gene screening and sequencing analysis. This […]