CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Monthly Archives: May 2023

Overview of Ribosomal RNA (rRNA)

What is ribosomal RNA? Ribosomal RNAs (rRNA) are the major components of ribosomes, which are responsible for protein synthesis by converting the instructions found in messenger RNA into the chains of amino acids. The key catalytic activity of ribosomes comes from the rRNAs. Additionally, rRNAs play an active role in recognizing conserved portions of mRNAs […]

Fact Sheet: Single Nucleotide Polymorphisms (SNPs)

What are SNPs? Single nucleotide polymorphisms, commonly called SNPs (pronounced “snips”), are the most frequent type of genetic variation among people, accounting for more than 90% of all differences between unrelated individuals. A SNP represents a difference in a single nucleotide. The DNA sequence contains four types of nucleotide bases: A (adenine), C (cytosine), G […]

New Human Pan-Genome Draft: An Additional 119 Million Base Pairs To Better Reflect Human Diversity!

The result of the Human Genome Project is a recognized "standard" for scientists – the reference genome. Like a coordinate system, researchers can better understand the structure, function, and variation of the human genome against the reference genome. The Human Genome Project began in 1990, the working draft was published in 2001, and the final […]

The First T2T Genome of Grape Provides New Insights into Its Genetic Breeding and Evolutionary Studies

Since the first human genome was published in 2000, many reference genomes have been assembled successively in various species. However, the highly repetitive sequences (telomeric, mitotic, ribosomal DNA) clustered in the genome have resulted in many missing fragments in the assembled genomes. Fortunately, thanks to improvements in sequencing technologies and computational algorithms, a new era […]

Integrative Genomic and Transcriptomic Analysis of Immunotherapy in Advanced NSCLC Using WES and RNA-seq

The use of PD-1/PD-L1 inhibitors has significantly improved overall survival in a subset of non-small cell lung cancer (NSCLC) patients, but only about 20% of patients respond to treatment. Identifying predictors of response is crucial to improve patient selection for immunotherapy. However, current understanding of relevant predictors is limited by the lack of large, multi-omic […]