Long Read Sequencing for Plant and Animal Microbiome

Pathogens in animals and plants affect their growth and health. Pathogen detection and characterization are key elements in the control of disease outbreaks in animals and plants. Genome sequencing aids in the diagnosis and characterization of animal and plant pathogens. As a leading genomic research company, CD Genomics provides comprehensive long read sequencing solutions to analyze the microbiota that affects the health, growth, and production of plants and animals, with the goal of improving crop yields and promoting livestock health and production.

Introduction to Plant and Animal Pathogens

Plant pathologists realize that plant diseases are controlled by multiple factors, such as the plant, the pathogen, and the environment (microbiome). Microorganisms that cause plant infectious diseases include fungi, oomycetes, bacteria, viruses, viroids, and virus-like organisms.

For farm animals, only a few viral diseases can cause significant economic losses. Examples include foot-and-mouth disease in cattle and pigs, classical swine fever and African swine fever in pigs, and avian influenza and Newcastle disease in poultry. Some livestock diseases are "zoonotic," meaning they cause illness in humans and animals. Examples include anthrax, tularemia, brucellosis, avian influenza, and Rift Valley fever caused by mosquito-borne viruses.

These microbiomes play a key role in animal and plant growth and health. Despite its importance, many fundamental questions about the microbiome remain largely unanswered.

Fig. 1. Pipelines for detection and identification of Calonectria pseudonaviculata (Cps). (Yang et al., 2022)

Solutions Offering at CD Genomics

CD Genomics provides specialized long read sequencing solutions for animal and plant microbiology to explore the biology of microbial symbionts, pathogens, microbiomes, and phytomes, and the role they play in crop yield, and livestock health. Our PacBio SMRT sequencing and ONT Nanopore sequencing platforms allow for the complete genetic characterization of animal and plant microbes to drive crop yields and promote livestock health and production.

Long read sequencing helps you gain a comprehensive understanding of the microbiota that impacts the health, growth ,and production of plants and animals. Our solutions enable researchers to:

• Generate Complete Genome Assemblies of Microorganisms

Conventional sequencing often fails to capture complete genomic landscapes, especially in regions rich in repetitive elements. Our long-read sequencing solutions ensure the elucidation of complete genome assemblies of plant and animal pathogens, leading to comprehensive insights into virulence factors, drug-resistance genes, and immune evasion strategies.

• Unravel Microbial Epigenetics

Beyond the genetic code, our solutions reveal microbial epigenetics. Understanding methylation patterns and their impact is critical to deciphering microbial behavior. Our approach provides a comprehensive understanding of how methylation affects key microbial traits, including host adaptation and inter-microbial competition.

• Track Resolved Viral Populations

The rapid mutation rates of viruses make tracking them particularly difficult. CD Genomics' powerful long read sequencing accurately resolves closely related viral strains, helping to provide insight into the emergence of toxic variants that threaten plant and animal evolution, transmission dynamics, and health.

• Characterize Microbial Communities

Ecosystem productivity and health depend on the synergistic interactions of plant biomes. By characterizing microbial communities in soil, water, and plant systems, our long read sequencing solutions provide insight into how these interactions affect overall ecosystem health and crop yields.

Advantages of Our Long Read Sequencing Solutions for Plant and Animal Microbiome

• A comprehensive view of the genome. By generating sequential reads, even the most complex regions can be accessed, ensuring a thorough understanding of the complexity of the genome.
• Improved accuracy. Reads generated with the CD Genomics solution maintain impeccable accuracy despite their length. This ensures that the data generated is not only comprehensive but also reliable, helping to make confident decisions in research and applications.
• Accommodate a wide range of samples. From diverse microbial communities in soil to complex animal gut microbiomes, our sequencing solutions are versatile and provide reliable results across multiple sample types.

CD Genomics is committed to using long read sequencing to analyze plant and animal microbiomes, helping to improve plant and animal disease diagnostics to control outbreaks in general. If you have any questions, please feel free to contact us. We look forward to working with you on projects of interest.

Related Services

PacBio SMRT Sequencing
Oxford Nanopore Sequencing
Microbial Whole-Genome Resequencing
Viral Whole-Genome Resequencing
Epigenetics and Methylation Analysis Using Long-Read Sequencing