We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy
Accept Cookies
With our advanced m6Am-Exo-seq technology, we provide in-depth analysis of m6Am modifications in RNA, unveiling its crucial role in gene expression regulation, translation efficiency, and other essential biological processes. CD Genomics offers an all-in-one solution for your research, ensuring efficient and accurate results from sample preparation to high-quality data delivery.
Whether you're conducting epitranscriptomic research or exploring areas such as oncology and immunology, our platform provides comprehensive RNA modification analysis to propel your scientific breakthroughs.
m6Am-Exo-seq Dual IP Library Construction Workflow
m6Am modification is an RNA modification located at the first base following the 5' cap in eukaryotic mRNA. It plays a significant role in gene expression regulation, mRNA stability, and translation control. With our m6Am-Exo-seq technology, researchers can precisely identify m6Am modification sites in both mRNA and lncRNA, and investigate their variations under different conditions.
Compared to traditional m6A modification analysis methods, m6Am-Exo-seq offers higher sensitivity and requires less sample input. Utilizing the Illumina HiSeq PE150 platform, we provide accurate modification site data for your research.
We offer a streamlined and efficient service process to ensure that every step meets the highest standards and guarantees flawless research data:
We work closely with clients to discuss research needs and customize experimental plans. We offer comprehensive technical consultation to optimize the research approach.
To ensure the accuracy of experimental results, we provide sample preparation and submission guidelines, supporting multiple sample types to ensure each sample meets experimental requirements.
Rigorous DNA quality checks and bisulfite treatment ensure the efficiency and accuracy of subsequent analyses.
Using the Illumina HiSeq PE150 platform, we perform efficient detection of m6Am modification sites and provide precise modification site data.
We offer customized bioinformatics analysis reports tailored to client needs, covering data quality control, differential modification analysis, functional annotation, and pathway analysis.
Our bioinformatics analysis service converts raw sequencing data into meaningful scientific results, facilitating key discoveries in your research. We provide comprehensive basic and advanced analysis modules, helping you interpret gene regulation and disease mechanisms from the perspective of m6Am modifications.
Our m6Am RNA modification analysis service is widely used across various research fields, enabling breakthroughs in multiple biological studies:
Identify m6Am modification differences between tumor and normal tissues, exploring the epigenetic mechanisms underlying cancer.
Delve into the regulatory roles of m6Am modifications during immune cell activation and differentiation.
Investigate the patterns of m6Am modifications in neurodegenerative diseases and brain development.
Uncover the role of m6Am modifications in epitranscriptomic regulation in various diseases.
To ensure the accuracy and high quality of m6Am RNA modification analysis, please prepare and submit samples according to the following guidelines:
| Sample Type | Key Requirements | Storage & Transport | Notes |
| Total RNA | ≥100 µg | Stored at -80°C, shipped on dry ice | Ensure high purity, free of RNAse contamination |
| Cell Samples | ≥5×10⁷ cells | Snap-frozen in liquid nitrogen, stored at -80°C, shipped on dry ice | Fresh or cultured cells accepted |
| Tissue Samples | ≥100 mg tissue or slices | Snap-frozen in liquid nitrogen, stored at -80°C, shipped on dry ice | Avoid repeated freeze-thaw cycles |
Species Limitation:
This service is limited to human and mouse species. For samples from other species, further evaluation is required to ensure suitability for analysis.
If your samples have specific requirements or you encounter any issues, please feel free to contact our expert team. We will provide comprehensive support and guidance.
Here are some publications by our clients who have used our Epigenomics and Epitranscriptomics sequencing services to enhance their research. These studies showcase the diverse applications of our services in fields like DNA methylation, gene regulation, and multi-omics research.
Our m6Am analysis service provides the following unique benefits, specifically designed to offer efficient, sensitive, and reliable epitranscriptomic analysis for researchers:
Our m6Am-Exo-seq technology enables high-precision analysis with minimal RNA sample input, significantly reducing experimental costs and conserving valuable sample resources.
Unlike traditional methods, m6Am-Exo-seq can simultaneously analyze m6Am modification sites in both mRNA and lncRNA, offering a comprehensive view of the complexity of the epitranscriptome.
We provide powerful bioinformatics support, including differential modification site identification, gene functional annotation, and enrichment analysis, allowing for in-depth interpretation of modifications under various biological conditions.
Our standardized workflow ensures high-quality data and rapid delivery, helping you achieve reliable research results in the shortest possible time.
Terms & Conditions Privacy Policy Copyright © CD Genomics. All rights reserved.