Knowledge Hub
ADMIXTURE vs STRUCTURE: Choosing K & Validating Results
Bacterial vs Eukaryotic Pangenomes: Methods, Sampling & Pitfalls
Big-Cohort Compute: Hail, plink2 & bigsnpr Basics
Biobank Sequencing Strategy: From Array to WGS
Building and Using Reference Libraries: BOLD & GenBank Best Practices
Case Study: LD-Based Marker Pruning Speeds a GWAS in Outbred Cohorts
Choosing Your ddRAD Pipeline: Stacks 2 vs ipyrad vs dDocent
Combining Reduced Representation Genome Sequencing with Imputation: When It Works and How to Validate
ddRAD for Plants: A Practical Manual for Non-Model Crops
ddRAD-Seq 101: Enzyme Choice & Size Selection
Designing ddRAD Projects: Expected Loci, Coverage Models & Budget
DNA Barcoding 101: Definition, Steps, and How It Works
DNA Barcoding in Plants: Choosing rbcL, matK, and ITS2
DNA Barcoding vs Metabarcoding: Which Fits Your Study?
fineSTRUCTURE & ChromoPainter: A Step-by-Step Guide
From LD to Tag SNPs: Building Efficient Panels Without Losing Power
GBS vs RAD vs ddRAD: Which Method Fits Your Project
Graph-based Pan-genome & Structural Variants 101
How Does DNA Barcoding Work? A Practical Workflow Guide
How Large-Scale Sequencing Supports Population Health Genomics
How to Choose a Variant Analysis Service for Large Cohorts
IBD & ROH: What They Reveal About Your Cohort
LD Decay and Haplotype Blocks: Interpreting Curves for Marker Strategy
LD-Based Ne vs PSMC for Population Dynamics: When to Use Which
Linkage Disequilibrium 101: What LD Measures and When It Matters
Linkage Equilibrium vs Disequilibrium: Concepts, Misconceptions, and Use-Cases
Low-Coverage WGS + ANGSD vs ddRAD: When to Replace, When to Complement
Low-Input & Non-Invasive Samples for RAD-seq: Feathers, Fin Clips, Feces, and Museum Specimens
Marker Selection Cheat Sheet: COI vs rbcL/matK vs ITS
Measuring Population Dynamics: Ne, Bottlenecks & Migration
Multiplexing & Coverage in Reduced Representation Genome Sequencing: Depth Targets, Missingness, and Power
Pan-genome Pipeline Deep Dive: From Annotation Harmonization to Orthology
Pan-genome Sampling Strategy: Humans, Animals, and Plants
Pan-genome Sequencing & Assembly: Short-reads vs HiFi/ONT and Hybrid
Pan-genome Tools at a Glance: Panaroo, Roary, PPanGGOLiN, PanX
Pan-genome vs Single Reference: Why One Genome Isn’t Enough
Pan-genome: Definition, Classification, and Why It Matters (2025 Guide)
Pangenome Explained: History, Sequencing Strategies, Databases, and Applications
PCA QC for GWAS: Outlier & Stratification Detection Guide
Planning Reduced Representation Sequencing in Non-Model Species: Genome Size, Repeats, and In-Silico Digest
Population Growth Trends in Genetics: Rare Variants, LD & GWAS Power
Population Structure Analysis Workflow: Reconciling PCA, ADMIXTURE, and Phylogenetic Trees from SNP Data
Population Structure with ddRAD: PCA, ADMIXTURE & STRUCTURE
Practical Guide: Designing an LD Study (MAF, r² Thresholds, Sample Size)
QC Metrics That Matter at Cohort Scale
Quality Control for Reduced Representation Sequencing: From Raw Reads to Reviewer-Proof SNP Sets
Reduced Representation Genome Sequencing at Cohort Scale: Batch Design, Bridge Samples, and Cross-Run Harmonization
Reduced Representation Sequencing (RRS): A Decision Guide for Population Genomics
Reference-Based vs De Novo Pipelines in Reduced Representation Genome Sequencing: Choosing a Workflow You Can Defend
Reporting & Interpretation: Match Scores, Thresholds, and Limitations
Reporting LD Results That Reviewers Accept: Plots, Thresholds, Pitfalls
Running LD the Right Way: PLINK Workflow, Parameters, and LD Pruning
Sample Collection, Preservation & Shipping for DNA Barcoding
Sampling & Batch Bias in Genomic Population Dynamics Studies
SNP Arrays vs Low-Pass and Deep WGS in Population Genomics
Troubleshooting DNA Barcoding: PCR Failures, Low Reads, and Contamination
Understanding RAD-seq: Principles, Workflows, and Best Practices
Using RAD-seq for Parentage Analysis and Population Assignment (PBT): Accuracy, SNP Panel Size, and Evaluation Methods
What Tools Analyze Population Structure
When Reduced Representation Sequencing Beats Low-Pass WGS (and When It Doesn't): A Budget-Realistic Framework