Revealing Antibiotic Resistance Genes with Whole-Genome Sequencing and Targeted Capture Methods
Antimicrobial resistance (AMR) is one of the most pressing challenges of the 21st century that poses a threat to modern society, resulting in largely increased morbidity, mortality, and economic costs.
Identifying and understanding AMR is essential for clinical practice to treat drug-resistant infections and for public health efforts to limit the spread of drug-resistant microorganisms. Technologies such as next-generation sequencing (NGS) are expanding our ability to detect and study antibiotic resistance genes. This infographic outlines the identification and characterization of antibiotic resistance genes using two NGS technologies: whole-genome sequencing (WGS) and targeted capture sequencing.
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