CDAMP® Pan-Cancer 500 Panel Kit


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CDAMP® Pan-Cancer 500 Panel Kit: pdf
CDAMP® Pan-Cancer 500 Panel Kit Gene List: pdf
Product Infomation
Product Description: CDAMP® Pan-Cancer 500 Panel Kit is specially designed for target enrichment and library preparation using a fast and simple workflow, in next generation sequencing (NGS) applications on Illumina platforms. The panel can be used to detect somatic variants and assessing tumor mutational burden (TMB) in tumor samples. The panel contains 27,296 amplicons covered a total of 516 genes associated with major solid tumor types and maintains >96% correlation with whole exome datasets. The Kit enables library preparation from as low as 10 ng genomic DNA per multiplex PCR reaction and allows a single library construction within 6 hours. This kit provides all required enzymes and buffers for Multiplex PCR Reaction, Purification, Indexing and Amplification. Magnetic beads can be used in library purification rapidly. The panel is optimized to deliver high specificity and highly coverage uniform sequencing results. All Kit components are subjected to stringent quality control ensuring the consistency and reproducibility of library preparation.
Features: Ready-to-use and containing all necessary reagents for a rapid set-up. Fast and streamlined workflow enables library construction in just 6 hours. Mutation detection on DNA amounts as low as 10 ng per multiplex PCR reaction. Excellent correlation( >96%) with whole exome datasets. Optimized to deliver high specificity (≥90%) and high coverage uniformity(≥95%) sequencing results. All Kit components are subjected to stringent quality control ensuring the consistency and reproducibility of library preparation.
Enrichment Method: Amplicon sequencing
Number of Genes: 516
Target Size: 1.64Mb
Amplicon Length : 105-120bp
Number of Primer Pools: 2
Sample Input Size : 10ng per pool for high quality gDNA; 20ng per pool for FFPE DNA
Species: human
Sample Type: Genomic DNA from whole blood, tissues, formalin-fixed paraffin-embedded (FFPE) tissues
Sequencing Platform: Illumina
Application: It is recommended to use this kit for: Tumor mutation burden(TMB) analysis Germline and somatic mutations (Single nucleotide variations, insertions-deletions)
Storage: All the components should be stored at -20℃.
* For Research Use Only. Not for use in diagnostic procedures.

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