CD Genomics Blog

Explore the blog we’ve developed, including genomic education, genomic technologies, genomic advances, and genomics news & views.

Blog Archives

CD Genomics Released A New Technology Called Single Cell Sequencing

Jun 7, 2016, single cell transcription and methylation analysis have become the powerful tools for single cell research. However, it is difficult to reveal the direct correlation between DNA methylation and gene expression in single cells. This is because there is a large difference between the cells, and we can not detect a cell’s transcription […]

Everyone Has His Own Little “Universe”

Every day we are dealing with countless microbes. But the latest research on a metagenomics shows that the microbial population on our skin surface is highly stable. These little guys are wrapping around us, like an invisible “little universe”. The bacteria, fungi and viruses on our skin are mostly harmless, and even healthy. But there […]

Three Companies for Exome Capture Efficiency Evaluation

Whole exome sequencing (WES) is now being used more and more in the field of research and diagnosis. Researchers are expected to study the entire coding regions of known genes with adequate sequencing depth and coverage. Currently a large number of exome capture platforms on the market have there respective advantages and some differences in […]

Improving Metagenomic Sequencing Significantly by Using the TruSPADES Method

Researchers from St. Petersburg State University developed a method to improve the sequencing ability of DNA greatly, like life microbes in the human gastrointestinal tract or the ocean bacteria in a new study. This TruSPADES method assembles the short reads from the 300 base pairs of Illumina machine through computer into synthetic long reads. The […]

Genotyping by PCR

Like many researchers to do hundreds of pieces of Southern blots, I first used PCR genotyping with soon efficiency. It no longer needed such as a few days to see the results and no longer needed DNA microscopic images or UV. With the continuous progress of technology, RCR makes the genomics and transcriptomics change dramatically, […]

Scientists Have Discovered A New Tumor Suppressor Gene

A common tumor suppressor gene was found in the patients with acute leukemia (AL). The finding reveals its synergistic effect between function abnormalities and a variety of different carcinogenic gene, providing an important foundation for research and development of novel leukemia treatment. Researchers found the transfer functional MLL – NRIP3 carcinogenic gene and SETD2 genetic […]

IncRNA for Gene Silencing in Plants

This is a review of lncRNA research in plants, which mainly describes the IncRNA regulation mechanism in siRNA mediated transcriptional gene silencing. There are two main ways: first, as siRNA precursor; second, activation of Long non-coding RNA transcription can help siRNA identify its target sites, which is involved in siRNA mediated DNA methylation. In addition, […]

What Do You Know About the Pacbio RS System

The PacBio RS system is the third generation sequencing platform based on the SMRT sequencing system which is invented by Pacific Biosciences company. It can do the job of sample preparation, sequencing and sequencing read in one day. It has some advantages that the second generation sequencing technology doesn’t have: splicing of a large amount […]

The Basic Information About SNP Genotyping of CD Genomics

What is SNP? SNP is the abbreviation of a single nucleotide polymorphism. It is the DNA sequence polymorphism caused by variation of single nucleotide, including the transition, transversion, insertion and deficiency of a single base. On average, one in 1,000 nucleotides in human genome is SNP. There are more than three million SNPs in the […]

The Application of Exome Sequencing in Disease Research

Exon is a part of eukaryotic genome sequence. The exome is the total of all exons, which takes one percent in the whole genome sequence of human beings. The exome sequencing is to capture and enrich the exome in the whole genome sequence by targeted capture, and get the genomic information by next generation sequencing. […]