Applied Biosystems SOLiD

The Applied Biosystems (AB) SOLiD System is a highly accurate, massively parallel genomic analysis platform that supports a wide range of applications. The flexibility of two independent flow cells and multiplexing capability allow researchers to conduct multiple experiments in a single run. With unparalleled throughput and greater than 99.94% basecalling accuracy, the SOLiD System enables researchers to complete large-scale sequencing and tag experiments more cost effectively than previously possible.

Highlights:

o Obtain more than 2 Gb of data per run
o High quality 35 bp reads generated with high confidence di-base encoding
o Single molecule clonal amplification of templates avoids cloning bias
o Ability to run up to 8 samples on separate channels
o Paired end library approaches
o Robust chemistry for accurate base-calling

Applications:

o De Novo Sequencing
o Targeted Resequencing
o Whole Genome resequencing
o Gene Expression profiling
o Small RNA analysis
o Whole Transcriptome Analysis
o Chromatin Immunoprecipitation (ChIP)
o Methylation Analysis