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Not all genes are active at all times. DNA methylation is a common epigenetic modification used by cells to regulate gene expression. In recent decades, researchers have discovered that methylation is involved in many cellular processes, including genomic imprinting, embryonic development, gene suppression, carcinogenesis, X-chromosome inactivation, and preservation of chromosome stability. And abnormal DNA methylation […]
Summary: a DNA methylation age inference method, combined with Sequenom MassARRAY technology, can reduce the error of the age to 4.7 years. Age estimation is one of the most important topics in the field of forensic medicine. Especially for juvenile delinquency, highly corrupt bones of the dead and nameless corpse, it can provide the scope […]
Except DNA and RNA, there are many messages which will affect the gene expression in genome. They do not change the sequence, but have the power of regulation on function and characteristics of gene by chemical modification, RNA interference and the interaction between protein and DNA. This change will be passed to the next generation. […]