CD Genomics proprietary GenSeqTM Technology provides exome and target region sequencing which overcome the challenges of working with large numbers of samples and regions, or demonstrated variable coverage.
Exome sequencing (also known as targeted exome capture) is an efficient strategy to selectively sequence the coding regions of the genome, which utilizes target enrichment strategy, as a cheaper but still effective alternative to whole genome sequencing.
Target region sequencing utilizes similar strategy which involves isolation of genomic regions of interest in a sample library, enabling cost effective and systematic detection of germline and somatic variants.
Exome and Target Region Sequencing Features and Benefits:
Targeted - focus on the regions of exome of interest.
Cost effective - much lower cost for narrowed region sequencing.
Precise - extremely high depth on the focused candidate sites or genes.
Exome and Target Region Sequencing Workflow:
Exome and Target Region Sequencing Applications:
Resequencing of exomic regions
Polygenic disease studies
Genetic marker development
Large genomic loci resequencing
Resequencing of candidate gene sets
Metabolic pathway studies
CD Genomics Exome and Target Region Sequencing Service include:
Raw data as FASTQ files
Base calling and demultiplexing
Alignment to reference sequence
On-target and coverage statistics
Annotated SNPs and small InDels